Грязные гены. "Большая стирка" для вашей ДНК. Как изменить свою наследственность - Бен Линч

30. Take folate instead of folic acid: Lynch, Ben. “Folic Acid and Pregnancy | Is Folic Acid the Right Choice?” You Tube, 7 September 2016, https://www.youtube.com/watch?v=tnVRv0zGsFY&t=603s.

31. In 1998, FDA required “enrichment” of foods: “Folate,” National Institutes of Health, Accessed April 2017, https://ods.od.nih.gov/factsheets/Folate-HealthProfessional/.

32. The wrong amount of exercise: Reynold, Gretchen. “How Exercise Changes Our DNA,” Well, 17 December 2014, https://well.blogs.nytimes.com/2014/12/17/how-exercise-changes-our-dna/?_r=1.

33. Poor Sleep: Kirkpatrick, Bailey. “The Epigenetics of Sleep: 3 Reasons to Catch More Zzz’s,” What is Epigenetics, 3 March 2015, http://www.whatisepigenetics.com/the-epigenetics-of-sleep-3-reasons-to-catch-more-zzzs/.

34. Methyl groups used faster under stress: Bing, Yuntao et al. “Glucocorticoid-induced S-Adenosylmethionine Enhances the Interferon Signaling Pathway by Restoring STAT1 Protein Methylation in Hepatitis B Virus-infected Cells,” The Journal of Biological Chemistry, 30 September 2014, http://www.jbc.org/content/289/47/32639.full.

3. Каков ваш генетический профиль?

35. COMT affects estrogen metabolism: Cussenot, Olivier. “Combination of Polymorphisms From Genes Related to Estrogen Metabolism and Risk of Prostate Cancers: The Hidden Face of Estrogens,” Journal of Clinical Oncology, August 2007, http://ascopubs.org/doi/full/10.1200/JCO.2007.11.0908.

4. Анкета № 1: каким генам необходима «чистка»?

5. MTHFR, или мастер метилирования

36. MTHFR SNP’s can lead to a decreased risk of colon cancer: Xie, SZ. et al. “Association between the MTHFR C677T polymorphism and risk of cancer: evidence from 446 case-control studies,” Tumour Biology, 17 June 2015, https://www.ncbi.nlm.nih.gov/pubmed/26081619.

37. If MTHFR is born dirty, it can have up to one hundred SNPS or even more: “MTHFR[all],” National Center for Biotechnology Information, U.S. National Library of Medicine, Accessed April 2017, https://www.ncbi.nlm.nih.gov/clinvar/?term=MTHFR[all].

38. Supports of healthy methylation: Wilcken, W. et al. “Geographical and ethnic variation of the 677C>T allele of 5,10 methylenetetrahydrofolate reductase (MTHFR): findings from over 7000 newborns from 16 areas world wide,” Journal of Medical Genetics, 2003, http://jmg.bmj.com/content/40/8/619.

39. Health Conditions Related to SNPs in Your MTHFR: “Genopedia: MTHFR,” Center for Disease Control and Prevention, Accessed April 2017, https://phgkb.cdc.gov/HuGENavigator/huGEPedia.do?firstQuery=MTHFR&geneID=4524&typeSubmit=GO&check=y&typeOption=gene&which=2&pubOrderType=pubD.

40. Cobalamin/B12 found in food: “Vitamin B₁₂,” Oregon State University Linus Pauling Institute Micronutrient Information Center, Accessed April 2017, http://lpi.oregonstate.edu/mic/vitamins/vitamin-B12#food-sources.

6. COMT. Внимательность и жизнерадостность, или спокойствие и отрешенность COMT

41. Catechols found in quercetin: “COMT Gene,” Genetic Home Reference, 11 April, 2017, https://ghr.nlm.nih.gov/gene/COMT#resources.

42. Dopamine quinone is associated with Parkinson’s disease and ADHD medications: Miyazak, Ikuko, Asanuma, Masato. “Approaches to Prevent Dopamine Quinone-Induced Neurotoxicity,” Neurochemical Research, 04 September 2008, http://link.springer.com/article/10.1007/s11064-008-9843-1.

43. Toxicity of Methylphenidate: Sadasivan, Shankar et al. “Methylphenidate Exposure Induces Dopamine Neuron Loss and Activation of Microglia in the Basal Ganglia of Mice,” PLOS One, 21 March 2012, http://journals.plos.org/plosone/article?id=79461.1371/journal.pone.0033693.

44. Toxicity of Methylphenidate: Espay, AJ. et al. “Methylphenidate for gait impairment in Parkinson disease,” American Academy of Neurology, 5 April 2011, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068005/.

45. Adderall can generate dopamine-quinone: German, Christopher L., Hanson, Glen R., Fleckenstein, Annette E., “Amphetamine and Methamphetamine Reduce Striatal Dopamine Transporter Function Without Concurrent Dopamine Transporter Relocalization,” Journal of Neurochemistry, 23 August 2012, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962019/.

46. Two common reasons for magnesium deficiency: Janett, S. et al. “Hypomagnesemia Induced by Long-Term Treatment with Proton-Pump Inhibitors,” Gastroentology Research & Practice, 4 May 2015, https://www.ncbi.nlm.nih.gov/pubmed/26064102.

47. Two common reasons for magnesium deficiency: Kynast-Gales, SA, Massey, LK. “Effect of caffeine on circadian excretion of urinary calcium and magnesium,” Journal of American College of Nutrition, October 1994, https://www.ncbi.nlm.nih.gov/pubmed/7836625.

48. Damage from dioxins: Liu, J. et al. “Variants in maternal COMT and MTHFR genes and risk of neural tube defects in offspring,” Metabolic Brain Disease, 4 July 2014, https://www.ncbi.nlm.nih.gov/pubmed/24990354.

49. Hugs raise dopamine: “The Power of Love Hugs and Cuddles Have Long-Term Effects,” NIH News In Health, February 2007, https://newsinhealth.nih.gov/2007/february/docs/01features_01.htm.

7. DAO: суперчувствительность к еде и токсинам

50. Where DAO enzymes lives in your body: “AOC1 Gene (Protein Coding),” Gene Cards, Accessed April 2017, http://www.genecards.org/cgi-bin/carddisp.pl?gene=AOC1#expression.